A contemporary review of management and prognostic factors of upper tract urothelial carcinoma. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Leow, Jeffrey J.; Orsola, Anna; Chang, Steven L.; Bellmunt, Joaquim
• Is Part Of: Cancer treatment reviews. Volume 41:Issue 4(2015)
• Page Start: 310
• Page End: 319
• Publication Date: 2015-04
• Subjects: Cancer -- Periodicals; Cancer -- Treatment -- Periodicals; Neoplasms -- therapy -- Periodicals; Cancer -- Périodiques; Cancer -- Traitement -- Périodiques; Cancer -- Treatment; Electronic journals; Periodicals; 616.99406
• DOI: 10.1016/j.ctrv.2015.02.006
• Languages: English
• ISSNs: 0305-7372

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st075">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0155">Gold-standard treatment for UTUC remains NU, increasingly performed using minimally invasive surgery, which still lacks long-term oncologic equivalency to open NU.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0160">Nomograms including pre- and post-operative variables can aid prognostication and guide further therapy.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0165">Peri-operative chemotherapy improves survival outcomes, and should be considered in eligible patients.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0170">Radiotherapy is of limited role, except for advanced pathologic stages with poor prognostic factors.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0175">Future therapies based on genomic alterations in urothelial cancers are on the horizon.</p> </list-item> </list> </p> </sec> </abstract>