Molecular histology of lung cancer: From targets to treatments. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Wood, Steven L.; Pernemalm, Maria; Crosbie, Philip A.; Whetton, Anthony D.
• Is Part Of: Cancer treatment reviews. Volume 41:Issue 4(2015)
• Page Start: 361
• Page End: 375
• Publication Date: 2015-04
• Subjects: Cancer -- Periodicals; Cancer -- Treatment -- Periodicals; Neoplasms -- therapy -- Periodicals; Cancer -- Périodiques; Cancer -- Traitement -- Périodiques; Cancer -- Treatment; Electronic journals; Periodicals; 616.99406
• DOI: 10.1016/j.ctrv.2015.02.008
• Languages: English
• ISSNs: 0305-7372

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="st165">Highlights</title> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0305">Genomic sequencing has identified key lung cancer driver mutations.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0310">These can provide both prognostic/diagnostic markers as well as potential drug targets.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0315">Molecular alterations inform targeted therapy options.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0320">Future directions: ctDNA and miRNA-based assays, as well as CSC profiling have potential to provide biological insight and markers.</p> </list-item> </list> </p> </sec> </abstract>