Genetic disposition and modifiable factors independently associated with anemia in patients with type 2 diabetes mellitus. Issue 1 (April 2015)

• Record Type: Journal Article
• Authors: Chiou, Terry Ting-Yu; Lee, Jong-Jer; Wang, Ming-Chung; Chung, Min-Shien; Pan, Lin-Lin; Hsieh, Ching-Jung; Huang, Siang-Ting; Chang, Hsueh-Wen; Yang, Kuender D.; Lee, Chien-Te; Liu, Rue-Tsuan
• Is Part Of: Diabetes research and clinical practice. Volume 108:Issue 1(2015)
• Page Start: 164
• Page End: 169
• Publication Date: 2015-04
• Subjects: Diabetes -- Periodicals; Diabetes Mellitus -- Periodicals; 616.462
• DOI: 10.1016/j.diabres.2014.12.012
• Languages: English
• ISSNs: 0168-8227

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005"> <italic>EPO</italic> promoter polymorphism is associated with anemia in patients with type 2 diabetes.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010"> <italic>ACE</italic> Insertion/Deletion and <italic>TNF-a G-308A</italic> were not associated with anemia.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Other risk factors: Age, duration of diabetes, renal function, and albuminuria.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020"> <italic>TT</italic> and <italic>TG</italic> genotypes in <italic>EPO</italic> were associated with 3–5-fold increased anemia risk.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">The <italic>EPO</italic> genotype may help identify patients at risk of anemia.</p> </list-item> </list> </p> </sec> </abstract>