Prevalence of human papilloma virus infection in patients with male accessory gland infection. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: La Vignera, S.; Vicari, E.; Condorelli, R.A.; Franchina, C.; Scalia, G.; Morgia, G.; Perino, A.; Schillaci, R.; Calogero, A.E.
• Is Part Of: Reproductive biomedicine online. Volume 30:Issue 4(2015)
• Page Start: 385
• Page End: 391
• Publication Date: 2015-04
• Subjects: Human reproductive technology -- Periodicals; Human embryo -- Periodicals; Reproduction -- Periodicals; 616.692
• DOI: 10.1016/j.rbmo.2014.12.016
• Languages: English
• ISSNs: 1472-6483

Abstract

<abstract abstract-type="author" id="ab0010"> <title id="st0010">Abstract</title> <sec> <p id="sp0010">The frequency of human papillomavirus (HPV) infection in the semen of patients with male accessory gland infection (MAGI) was evaluated. One hundred infertile patients with MAGI were classified into group A: patients with an inflammatory MAGI (<italic>n</italic> = 48) and group B: patients with a microbial form (<italic>n</italic> = 52). Healthy age-matched fertile men (34.0 ± 4.0 years) made up the control group (<italic>n</italic> = 20). Amplification of HPV DNA was carried out by HPV-HS Bio nested polymerase chain reaction for the detection of HPV DNA sequences within the L1 ORF. Ten patients in group A (20.8%) and 15 patients in group B (28.8%) had a HPV infection; two controls (10.0%) had HPV infection. Patients with MAGI had a significantly higher frequency of HPV infection compared with controls; patients with a microbial MAGI had significantly higher frequency of HPV infection compared with patients with an inflammatory form (both <italic>P</italic> &lt; 0.05). Patients with MAGI and HPV had a slight, but significantly lower sperm progressive motility and normal morphology compared with patients with MAGI HPV-negative (<italic>P</italic> &lt; 0.05). Elevated frequency of HPV infection occurred in patients with MAGI, suggesting that HPV should be investigated in the diagnostic work-up of these patients.</p> </sec> </abstract>