Somatosensory and motor evoked potentials as biomarkers for post-operative neurological status. Issue 5 (May 2015)

• Record Type: Journal Article
• Authors: Holdefer, R.N.; MacDonald, D.B.; Skinner, S.A.
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 5(2015:May)
• Page Start: 857
• Page End: 865
• Publication Date: 2015-05
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2014.11.009
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st110">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0215">Intraoperative evoked potentials (EPs) are often used during surgery as surrogates for true clinical endpoints.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0220">A three step framework recently proposed by the Institute of Medicine was used to evaluate EP biomarkers as surrogate endpoints.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0225">Causality guidelines and contingency analysis provided partial validation of EP surrogates.</p> </list-item> </list> </p> </sec> </abstract>