Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl amides as potent and long acting muscarinic antagonists. Issue 8 (15th April 2015)

• Record Type: Journal Article
• Authors: Prat, Maria; Buil, María Antonia; Fernández, Maria Dolors; Tort, Laia; Monleón, Juan Manuel; Casals, Gaspar; Ferrer, Manuel; Castro, Jordi; Gavaldà, Amadeu; Miralpeix, Montserrat; Ramos, Israel; Vilella, Dolors; Huerta, Josep Maria; Espinosa, Sònia; Hernández, Begoña; Segarra, Victor; Córdoba, Mònica
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 25:Issue 8(2015)
• Page Start: 1736
• Page End: 1741
• Publication Date: 2015-04-15
• Subjects: Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.02.065
• Languages: English
• ISSNs: 0960-894X

Abstract

<abstract xml:lang="en" abstract-type="graphical" id="ab005"> <title id="st005">Graphical abstract</title> <sec> <p id="sp0005">SAR around R¹, R² and R³ are reported. <fig id="f0055" position="anchor"><graphic position="anchor" xlink:href="ark:/27927/pgjcxvb361" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></fig></p> </sec> </abstract>