Alternative delivery of a thermostable inactivated polio vaccine. Issue 17 (21st April 2015)

• Record Type: Journal Article
• Authors: Kraan, Heleen; Ploemen, Ivo; van de Wijdeven, Gijsbert; Que, Ivo; Löwik, Clemens; Kersten, Gideon; Amorij, Jean-Pierre
• Is Part Of: Vaccine. Volume 33:Issue 17(2015)
• Page Start: 2030
• Page End: 2037
• Publication Date: 2015-04-21
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.03.011
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Potential of Bioneedle technology for inactivated polio vaccine (IPV) was evaluated.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">IPV in Bioneedles is more resistant to elevated temperatures than liquid IPV.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Comparable immunogenicity of IPV-Bioneedle and liquid IPV after booster vaccination.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Similar kinetics at administration site for Bioneedle compared to liquid injection.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">LPS-derivate PagL is potent adjuvant for liquid IPV, not for IPV-Bioneedles.</p> </list-item> </list> </p> </sec> </abstract>