Human sebum extract induces barrier disruption and cytokine expression in murine epidermis. Issue 1 (April 2015)

• Record Type: Journal Article
• Authors: Guo, Jiun-Wen; Lin, Tzu-Kai; Wu, Chin-Han; Wei, Kai-Che; Lan, Cheng-Che E.; Peng, Amy Chia-Ying; Tsai, Jui-Chen; Sheu, Hamm-Ming
• Is Part Of: Journal of dermatological science. Volume 78:Issue 1(2015:Apr.)
• Page Start: 34
• Page End: 43
• Publication Date: 2015-04
• Subjects: Dermatology -- Periodicals; Skin Diseases -- Periodicals; Dermatologie -- Périodiques; 616.5005
• DOI: 10.1016/j.jdermsci.2015.01.010
• Languages: English
• ISSNs: 0923-1811

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Sebum imparts detrimental effects on skin permeability barrier of hairless mice.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Skin barrier disruption by sebum elicits an epidermal inflammatory cascade.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Sebum-induced dermatitis resembles irritant contact dermatitis.</p> </list-item> </list> </p> </sec> </abstract>