The effect of Indomethacin and Betamethasone on the cytokine response of human neonatal mononuclear cells to gram-positive bacteria. Issue 1 (May 2015)

• Record Type: Journal Article
• Authors: Ernst, Wolfgang; Kusi, Evelyn; Fill Malfertheiner, Sara; Reuschel, Edith; Deml, Ludwig; Seelbach-Göbel, Birgit
• Is Part Of: Cytokine. Volume 73:Issue 1(2015)
• Page Start: 91
• Page End: 100
• Publication Date: 2015-05
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.01.023
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st050">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0110">The effect of different drugs on the cytokine expression of CBMC after stimulation was evaluated.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0115">Betamethasone decreased production of pro-inflammatory cytokines.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0120">Indomethacin increased IL-10 production.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0125">A combination of both had a similar effect as Betamethasone alone.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0130">The cytokine expression differed depending on the gram-positive pathogen used for stimulation.</p> </list-item> </list> </p> </sec> </abstract>