Quantifying maternally derived respiratory syncytial virus specific neutralising antibodies in a birth cohort from coastal Kenya. Issue 15 (8th April 2015)

• Record Type: Journal Article
• Authors: Nyiro, Joyce U.; Sande, Charles; Mutunga, Martin; Kiyuka, Patience K.; Munywoki, Patrick K.; Scott, J. Anthony G.; Nokes, D James
• Is Part Of: Vaccine. Volume 33:Issue 15(2015)
• Page Start: 1797
• Page End: 1801
• Publication Date: 2015-04-08
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2015.02.039
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We report on the characteristics of RSV neutralising antibodies in a birth cohort.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The levels of cord RSV antibodies increase during seasonal virus transmission.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">The rate of decay of RSV antibodies following birth is independent of cord titre.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">There is a high degree of variation between individuals in rate of decay.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Important baseline data to maternal RSV vaccine development are provided.</p> </list-item> </list> </p> </sec> </abstract>