Identification of Type I IFN in Chinese giant salamander (Andrias davidianus) and the response to an iridovirus infection. Issue 2 (June 2015)

• Record Type: Journal Article
• Authors: Chen, Qian; Ma, Jie; Fan, Yuding; Meng, Yan; Xu, Jin; Zhou, Yong; Liu, Wenzhi; Zeng, Xianhui; Zeng, Lingbing
• Is Part Of: Molecular immunology. Volume 65:Issue 2(2015:Jun.)
• Page Start: 350
• Page End: 359
• Publication Date: 2015-06
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.02.015
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">This is the first report of the identification and characterization of typeIIFN in the Chinese giant salamander.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Identification of the C-terminal CAWE motif in Chinese giant salamander typeIIFN.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Chinese giant salamander typeIIFN was significantly induced by poly I:C and giant salamander iridovirus (GSIV) infection in peripheral blood leucocytes.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">The <italic>in vitro</italic> anti-viral function of the Chinese giant salamander typeIIFN was demonstrated for the first time.</p> </list-item> </list> </p> </sec> </abstract>