The synergistic effect of combination temozolomide and chloroquine treatment is dependent on autophagy formation and p53 status in glioma cells. Issue 2 (1st May 2015)

• Record Type: Journal Article
• Authors: Lee, Seung Woo; Kim, Hyun-Kyung; Lee, Na-Hyeon; Yi, Hee-Yeon; Kim, Hong-Sug; Hong, Sung Hee; Hong, Yong-Kil; Joe, Young Ae
• Is Part Of: Cancer letters. Volume 360:Issue 2(2015)
• Page Start: 195
• Page End: 204
• Publication Date: 2015-05-01
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.02.012
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Combination of temozolomide and chloroquine creates a synergistic effect.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">The synergistic effect from combination treatment of temozolomide and chloroquine is dependent on autophagy.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">The pro-apopototic effect from combination treatment of temozolomide and chloroquine is dependent on p53.</p> </list-item> </list> </p> </sec> </abstract>