Blockage of LMP1-modulated store-operated Ca2+ entry reduces metastatic potential in nasopharyngeal carcinoma cell. Issue 2 (1st May 2015)

• Record Type: Journal Article
• Authors: Wei, Jiazhang; Zhang, Jinyan; Si, Yongfeng; Kanada, Masamitsu; Zhang, Zhe; Terakawa, Susumu; Watanabe, Hiroshi
• Is Part Of: Cancer letters. Volume 360:Issue 2(2015)
• Page Start: 234
• Page End: 244
• Publication Date: 2015-05-01
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.02.032
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Two <italic>in vivo</italic> models, mice and transgenic zebrafishes, were employed into the present study.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">The circulating LMP1-expressing cells arrested in a small-caliber vessel actively mobilized surrounding endothelial cells.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">We propose that EBV-encoded LMP1 endows NPC cell with aggressive properties by boosting SOCE.</p> </list-item> </list> </p> </sec> </abstract>