Epileptic focus localization based on resting state interictal MEG recordings is feasible irrespective of the presence or absence of spikes. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Krishnan, B.; Vlachos, I.; Wang, Z.I.; Mosher, J.; Najm, I.; Burgess, R.; Iasemidis, L.; Alexopoulos, A.V.
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 4(2015:Apr.)
• Page Start: 667
• Page End: 674
• Publication Date: 2015-04
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2014.07.014
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st160">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0195">For the first time a connectivity-based analysis of MEG data is tested for epileptogenic focus localization in patients with neocortical epilepsy.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0200">MEG recordings from five patients with medically-intractable focal epilepsy undergoing presurgical evaluation for resection of candidate epileptic focus were analyzed.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0205">Proposed algorithm can localize the epileptogenic focus accurately even in patients with normal MRI (MRI-negative) or patients without interictal abnormalities on scalp EEG (EEG-negative) or MEG (MEG-negative).</p> </list-item> </list> </p> </sec> </abstract>