Immunology of bovine respiratory syncytial virus in calves. Issue 1 (July 2015) - Guzman, Efrain
Highlights BRSV in calves can be used as a model for RSV infection in infants. As a natural host, BRSV interacts with PPRs in bovine cells in an authentic way. The calf model of BRSV can be used to dissect mechanisms of immunopathogenesis. F-specific, neutralising antibodies and CD8+ T cells are important in protection. Lymphatic cannulation of calves can be used to analyse regional immune responses.