Human papillomavirus status and p16INK4A expression in patients with mucosal squamous cell carcinoma of the head and neck in Queensland, Australia. Issue 2 (April 2015)

• Record Type: Journal Article
• Authors: Antonsson, Annika; Neale, Rachel E.; Boros, Samuel; Lampe, Guy; Coman, William B.; Pryor, David I.; Porceddu, Sandro V.; Whiteman, David C.
• Is Part Of: Cancer epidemiology. Volume 39:Issue 2(2015)
• Page Start: 174
• Page End: 181
• Publication Date: 2015-04
• Subjects: Cancer -- Epidemiology -- Periodicals; Cancer -- Prevention -- Periodicals; Cancer -- Diagnosis -- Periodicals; Carcinogenesis -- Periodicals; 616.994005
• DOI: 10.1016/j.canep.2015.01.010
• Languages: English
• ISSNs: 1877-7821

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">HPV prevalence in Australian HNSCCs and HPV affected cell-cycle regulation.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Gender and alcohol consumption not associated with HPV or p16 status.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Predictors of HPV-positivity were younger age (&lt;60 years) and non-moderate smoking.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">High concordance between HPV/p16 status with a kappa of 0.72.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Despite high concordance, we found 11% being discordant for HPV/p16 status.</p> </list-item> </list> </p> </sec> </abstract>