The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT–mTOR signaling pathway. Issue 1 (28th April 2015)

• Record Type: Journal Article
• Authors: Zhou, Wei; He, Mei-Rong; Jiao, Hong-Li; He, Liu-Qing; Deng, Dan-Ling; Cai, Juan-Juan; Xiao, Zhi-Yuan; Ye, Ya-Ping; Ding, Yan-Qing; Liao, Wen-Ting; Liu, Si-De
• Is Part Of: Cancer letters. Volume 360:Issue 1(2015)
• Page Start: 68
• Page End: 75
• Publication Date: 2015-04-28
• Subjects: Cancer -- Periodicals; Neoplasms -- Periodicals; Cancer -- Périodiques; Electronic journals; 616.994
• DOI: 10.1016/j.canlet.2015.02.004
• Languages: English
• ISSNs: 0304-3835

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">Decreased expression of LZTS1 was correlated to aggressive characteristics and poor survival of patients with colorectal cancer.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">LZTS1 inhibits colorectal cancer cell proliferation and tumor growth.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">LZTS1 inhibited cell proliferation and tumor growth in colorectal cancer partially via suppression of AKT–mTOR signaling.</p> </list-item> </list> </p> </sec> </abstract>