Surgical treatment for mono-segmental lumbar tuberculosis by single-stage posterior debridement, compact bone grafting and posterior single-segment fixation. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Xu, Zhengquan; Wang, Xiyang; Wu, Ping; Pang, Xiaoyang; Luo, Chengke; Zhang, Penghui; Zeng, Hao; Peng, Wei
• Is Part Of: Injury. Volume 46:Issue 7(2015)
• Page Start: 1311
• Page End: 1316
• Publication Date: 2015-07
• Subjects: Wounds and injuries -- Surgery -- Periodicals; Accidents -- Periodicals; Wounds and Injuries -- surgery -- Periodicals; Lésions et blessures -- Chirurgie -- Périodiques; Electronic journals; Electronic journals; 617.1
• DOI: 10.1016/j.injury.2015.03.023
• Languages: English
• ISSNs: 0020-1383

Abstract

<abstract abstract-type="author" id="abs0005"> <title id="sect0005">Abstract</title> <sec> <title id="sect0010">Purpose</title> <p id="spar0005">To evaluate the efficacy and safety of single-stage posterior debridement, compact bone grafting and posterior single-segment fixation for the treatment of mono-segmental lumbar tuberculosis.</p> </sec> <sec> <title id="sect0015">Methods</title> <p id="spar0010">We enrolled 32 patients with mono-segmental lumbar tuberculosis from January 2005 to April 2011. The severity of damage to the vertebral bodies is not more than 2/3 height. All the patients were treated by single-stage posterior debridement, compact bone grafting and posterior single-segment fixation.</p> </sec> <sec> <title id="sect0020">Results</title> <p id="spar0015">Patients were followed 21–63 months (43.5 ± 9.5 months). The average Cobb angle decreased to 5.3 ± 3.0° postoperatively from 22.1 ± 6.1° preoperatively. Meanwhile, average 1.8 ± 1.0° loss was observed at last visit. Fusion occurred at 3–9 months (mean 5.1 months). All patients with preoperative neurologic deficit recovered in different degree. 1 with grade B recovered to grade D; 2 with grade C recovered to grade E; 18 with grade D recovered to grade E. No mortality occurred. One patient experienced anti-tuberculosis drug-induced liver dysfunction which was managed successfully with modified anti-TB treatment and hepato-protective treatment. The Oswestry Disability Index decreased from 40.1 ± 4.0 preoperatively to 13.7 ± 3.1 postoperatively.</p> </sec> <sec> <title id="sect0025">Conclusions</title> <p id="spar0020">Single-stage posterior debridement, compact bone grafting and posterior single-segment fixation is an effective method for the treatment of mono-segmental lumbar tuberculosis.</p> </sec> </abstract>