Cynaropicrin attenuates UVB-induced oxidative stress via the AhR–Nrf2–Nqo1 pathway. Issue 2 (16th April 2015)

• Record Type: Journal Article
• Authors: Takei, Kenjiro; Hashimoto-Hachiya, Akiko; Takahara, Masakazu; Tsuji, Gaku; Nakahara, Takeshi; Furue, Masutaka
• Is Part Of: Toxicology letters. Volume 234:Issue 2(2015)
• Page Start: 74
• Page End: 80
• Publication Date: 2015-04-16
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2015.02.007
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0030"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005"> <italic>Artichoke</italic> is known for its antioxidant and anti-inflammatory activities.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Cynaropicrin is a major bioactive phytochemical in the <italic>artichoke</italic>.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Cynaropicrin activates AhR–Nrf2–Nqo1 antioxidant pathway.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Antioxidant cynaropicrin attenuates ultraviolet B-induced oxydation in keratinocytes.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Antioxidant cynaropicrin potently inhibits the production of IL-6 and TNFα.</p> </list-item> </list> </p> </sec> </abstract>