Aspergillus flavus induces granulomatous cerebral aspergillosis in mice with display of distinct cytokine profile. Issue 2 (April 2015)

• Record Type: Journal Article
• Authors: Anand, R.; Shankar, J.; Tiwary, B.N.; Singh, A.P.
• Is Part Of: Cytokine. Volume 72:Issue 2(2015)
• Page Start: 166
• Page End: 172
• Publication Date: 2015-04
• Subjects: Cytokines -- Periodicals; 571.844
• DOI: 10.1016/j.cyto.2015.01.006
• Languages: English
• ISSNs: 1043-4666

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st095">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0130">Histological study exhibited hyphae with leukocyte infiltrations forming granuloma.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0135">Ischemia and pyknosis of neurons in the brain of infected mice was observed.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0140">Infected mice displayed increased secretion of Th1 cytokines during late phase.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0145">Reduced secretion of IL-4 and IL-23 was concomitant with Th1 cytokines profile.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0150"> <italic>Aspergillus flavus</italic> induced inflammatory granulomatous cerebral aspergillosis.</p> </list-item> </list> </p> </sec> </abstract>