Molecular drivers of cellular metabolic reprogramming in melanoma. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Abildgaard, Cecilie; Guldberg, Per
• Is Part Of: Trends in molecular medicine. Volume 21:Issue 3(2015)
• Page Start: 164
• Page End: 171
• Publication Date: 2015-03
• Subjects: Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; Physiology, Pathological -- Periodicals; 572.8
• DOI: 10.1016/j.molmed.2014.12.007
• Languages: English
• ISSNs: 1471-4914

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Profound changes in cellular metabolism are a hallmark of melanoma.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Rewiring of metabolism is controlled by known melanoma drivers.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Metabolic changes in melanoma represent new targets for therapeutic intervention.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Treatment effectiveness may depend on genetic drivers and mitochondrial performance.</p> </list-item> </list> </p> </sec> </abstract>