Efficacy of panobinostat and marizomib in acute myeloid leukemia and bortezomib-resistant models. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Corrales-Medina, Fernando F.; Manton, Christa A.; Orlowski, Robert Z.; Chandra, Joya
• Is Part Of: Leukemia research. Volume 39:Issue 3(2015:Mar.)
• Page Start: 371
• Page End: 379
• Publication Date: 2015-03
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2014.12.014
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Panobinostat elicits cell death in acute myeloid leukemia (AML) cell lines.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Cell lines resistant to proteasome inhibitors are sensitive to panobinostat.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Synergy is observed with panobinostat and proteasome inhibitors in AML lines.</p> </list-item> </list> </p> </sec> </abstract>