Hemoglobin levels and circulating blasts are two easily evaluable diagnostic parameters highly predictive of leukemic transformation in primary myelofibrosis. Issue 3 (March 2015)

• Record Type: Journal Article
• Authors: Rago, Angela; Latagliata, Roberto; Montanaro, Marco; Montefusco, Enrico; Andriani, Alessandro; Crescenzi, Sabrina Leonetti; Mecarocci, Sergio; Spirito, Francesca; Spadea, Antonio; Recine, Umberto; Cicconi, Laura; Avvisati, Giuseppe; Cedrone, Michele; Breccia, Massimo; Porrini, Raffaele; Villivà, Nicoletta; De Gregoris, Cinzia; Alimena, Giuliana; D'Arcangelo, Enzo; Guglielmelli, Paola; Lo-Coco, Francesco; Vannucchi, Alessandro; Cimino, Giuseppe
• Is Part Of: Leukemia research. Volume 39:Issue 3(2015:Mar.)
• Page Start: 314
• Page End: 317
• Publication Date: 2015-03
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.01.001
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We presented an easy score to predict leukemic transformation in PMF.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The model is based on anemia and circulating blasts.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Two groups were defined, low (none/one parameter) vs high risk (both parameters).</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0135">The study included a validation cohort.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0140">These data could be useful for institutions of developing countries.</p> </list-item> </list> </p> </sec> </abstract>