Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles. Issue 2 (4th March 2015)

• Record Type: Journal Article
• Authors: Bajak, Edyta; Fabbri, Marco; Ponti, Jessica; Gioria, Sabrina; Ojea-Jiménez, Isaac; Collotta, Angelo; Mariani, Valentina; Gilliland, Douglas; Rossi, François; Gribaldo, Laura
• Is Part Of: Toxicology letters. Volume 233:Issue 2(2015)
• Page Start: 187
• Page End: 199
• Publication Date: 2015-03-04
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2014.12.008
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0055"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Biological effects (toxicity, uptake and changes in gene expression patterns) on Caco-2 cells of citrate-stabilized 5 nm and 30 nm AuNPs were compared.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Exposure to 5 nm AuNPs had much stronger effect on gene expression as compared to treatment with 30 nm AuNPs.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Nrf2 signaling stress response was among the highly activated pathways.</p> </list-item> </list> </p> </sec> </abstract>