Benign (BI-RADS 2) lesions in breast MRI. Issue 4 (April 2015)

• Record Type: Journal Article
• Authors: Spick, C.; Szolar, D.H.M.; Tillich, M.; Reittner, P.; Preidler, K.W.; Baltzer, P.A.
• Is Part Of: Clinical radiology. Volume 70:Issue 4(2015)
• Page Start: 395
• Page End: 399
• Publication Date: 2015-04
• Subjects: Medical radiology -- Periodicals; Radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiology -- Periodicals; Societies, Medical -- Periodicals; Medical radiology; Radiotherapy; Electronic journals; Periodicals; 616.0757
• DOI: 10.1016/j.crad.2014.12.004
• Languages: English
• ISSNs: 0009-9260

Abstract

<abstract xml:lang="en" abstract-type="author" id="abs0010"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <title id="sectitle0010">Aim</title> <p id="abspara0010">To assess the frequency of malignancy in lesions characterized as benign [Breast Imaging—Reporting and Data System (BI-RADS) 2] on breast MRI.</p> </sec> <sec> <title id="sectitle0015">Materials and methods</title> <p id="abspara0015">In this institutional review board-approved retrospective single-centre study, 1265 consecutive patients (mean age 50±13 years), undergoing dynamic contrast-enhanced MRI (1.5 T) of the breast during a 6 year time period, were eligible. This study investigated the MRI characteristics and frequency of malignancy in 192 of these patients with breast lesions classified as BI-RADS 2. Examinations were read during clinical practice and classified according to the MRI BI-RADS lexicon. Based on the patient's and referring physician's preferences, lesions were either histopathologically verified or were subjected to both clinical and imaging follow-up of at least 2 years (range 2–9 years). Descriptive statistical metrics were calculated.</p> </sec> <sec> <title id="sectitle0020">Results</title> <p id="abspara0020">According to the standard of reference, 0 of 192 (0%) lesions classified as BI-RADS 2 were malignant. Histopathology was available in 67 (34.9%) lesions and revealed benign findings exclusively. The remaining 125 (65.1%) lesions did not exhibit changes during the follow-up period and were, therefore, considered negative for malignancy.</p> </sec> <sec> <title id="sectitle0025">Conclusions</title> <p id="abspara0025">The frequency of malignancy in breast lesions classified as BI-RADS 2 is zero. As a consequence, breast biopsies are unnecessary in these cases.</p> </sec> </abstract>