Molecular characterization of a peptidoglycan recognition protein from the cotton bollworm, Helicoverpa armigera and its role in the prophenoloxidase activation pathway. Issue 1 (May 2015)

• Record Type: Journal Article
• Authors: Li, Yu-Ping; Xiao, Min; Li, Li; Song, Cai-Xia; Wang, Jia-Lin; Liu, Xu-Sheng
• Is Part Of: Molecular immunology. Volume 65:Issue 1(2015:May)
• Page Start: 123
• Page End: 132
• Publication Date: 2015-05
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2015.01.016
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">HaPGRP-A can bind and agglutinate bacteria.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">HaPGRP-A is involved in the PPO activation pathway.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">HaPGRP-A is involved in the melanization process of nodulation and encapsulation.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Knockdown of <italic>HaPGRP-A</italic> decreased PO activity in bacteria-challenged larval hemolymph.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">RNAi-treated larvae showed increased bacterial growth in the hemolymph.</p> </list-item> </list> </p> </sec> </abstract>