Acute callosal disconnection syndrome as an initial manifestation of neuromyelitis optica spectrum disorders. Issue 4 (26th January 2015)

• Record Type: Journal Article
• Authors: Kobayashi, Junpei; Kuroda, Hiroshi; Ezura, Michinori; Sugeno, Naoto; Shibui, Aya; Takahashi, Toshiyuki; Misu, Tatsuro; Fujihara, Kazuo; Mori, Etsuro; Aoki, Masashi
• Is Part Of: Neurology and clinical neuroscience. Volume 3:Issue 4(2015)
• Page Start: 137
• Page End: 139
• Publication Date: 2015-01-26
• Subjects: Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8
• DOI: 10.1111/ncn3.164
• Languages: English
• ISSNs: 2049-4173

Abstract

<abstract abstract-type="main" id="ncn3164-abs-0001"> <title>Abstract</title> <p>We present a 76‐year‐old ambidextrous man with acute callosal disconnection syndrome accompanied by acquired stuttering and right hemiparesis. Brain magnetic resonance imaging showed edematous pancallosal lesions and a spotty lesion in the left precentral gyrus. We diagnosed him as having neuromyelitis optica spectrum disorders according to the seropositivity for anti‐aquaporin‐4 antibody. Callosal disconnection syndrome presented unique laterality as a result of ambidexterity, and was outstanding even during the acute attack as a result of massive and selective corpus callosum involvement. Measurement of anti‐aquaporin‐4 antibody can be useful for differential diagnosis of patients presenting acute callosal disconnection syndrome.</p> </abstract>