K‐t FASTER: Acceleration of functional MRI data acquisition using low rank constraints. Issue 2 (28th August 2014)

• Record Type: Journal Article
• Authors: Chiew, Mark; Smith, Stephen M.; Koopmans, Peter J.; Graedel, Nadine N.; Blumensath, Thomas; Miller, Karla L.
• Is Part Of: Magnetic resonance in medicine. Volume 74:Issue 2(2015:Aug.)
• Page Start: 353
• Page End: 364
• Publication Date: 2014-08-28
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25395
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm25395-sec-0001" sec-type="section"> <title>Purpose</title> <p>In functional MRI (fMRI), faster sampling of data can provide richer temporal information and increase temporal degrees of freedom. However, acceleration is generally performed on a volume‐by‐volume basis, without consideration of the intrinsic spatio‐temporal data structure. We present a novel method for accelerating fMRI data acquisition, k‐t FASTER (FMRI Accelerated in Space‐time via Truncation of Effective Rank), which exploits the low‐rank structure of fMRI data.</p> </sec> <sec id="mrm25395-sec-0002" sec-type="section"> <title>Theory and Methods</title> <p>Using matrix completion, 4.27× retrospectively and prospectively under‐sampled data were reconstructed (coil‐independently) using an iterative nonlinear algorithm, and compared with several different reconstruction strategies. Matrix reconstruction error was evaluated; a dual regression analysis was performed to determine fidelity of recovered fMRI resting state networks (RSNs).</p> </sec> <sec id="mrm25395-sec-0003" sec-type="section"> <title>Results</title> <p>The retrospective sampling data showed that k‐t FASTER produced the lowest error, approximately 3–4%, and the highest quality RSNs. These results were validated in prospectively under‐sampled experiments, with k‐t FASTER producing better identification of RSNs than fully sampled acquisitions of the same duration.</p> </sec> <sec id="mrm25395-sec-0004" sec-type="section"> <title>Conclusion</title> <p>With k‐t FASTER, incoherently under‐sampled fMRI data can be robustly recovered using only rank constraints. This technique can be used to improve the speed of fMRI sampling, particularly for multivariate analyses such as temporal independent component analysis. Magn Reson Med 74:353–364, 2015. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>