Fast 3D T2‐weighted imaging using variable flip angle transition into driven equilibrium (3D T2‐TIDE) balanced SSFP for prostate imaging at 3T. Issue 2 (5th September 2014)

• Record Type: Journal Article
• Authors: Srinivasan, Subashini; Wu, Holden H.; Sung, Kyunghyun; Margolis, Daniel J.A.; Ennis, Daniel B.
• Is Part Of: Magnetic resonance in medicine. Volume 74:Issue 2(2015:Aug.)
• Page Start: 442
• Page End: 451
• Publication Date: 2014-09-05
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.25430
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm25430-sec-0001" sec-type="section"> <title>Purpose</title> <p>Three‐dimensional (3D) T<sub>2</sub>‐weighted fast spin echo (FSE) imaging of the prostate currently requires long acquisition times. Our objective was to develop a fast 3D T<sub>2</sub>‐weighted sequence for prostate imaging at 3T using a variable flip angle transition into driven equilibrium (T<sub>2</sub>‐TIDE) scheme.</p> </sec> <sec id="mrm25430-sec-0002" sec-type="section"> <title>Methods</title> <p>3D T<sub>2</sub>‐TIDE uses interleaved spiral‐out phase encode ordering to efficiently sample the k<sub>y</sub>–k<sub>z</sub> phase encodes and also uses the transient balanced steady‐state free precession signal to acquire the center of k‐space for T<sub>2</sub>‐weighted imaging. Bloch simulations and images from 10 healthy subjects were acquired to evaluate the performance of 3D T<sub>2</sub>‐TIDE compared to 3D FSE.</p> </sec> <sec id="mrm25430-sec-0003" sec-type="section"> <title>Results</title> <p>3D T<sub>2</sub>‐TIDE images were acquired in 2:54 minutes compared to 7:02 minutes for 3D FSE with identical imaging parameters. The signal‐to‐noise ratio (SNR) efficiency was significantly higher for 3D T<sub>2</sub>‐TIDE compared to 3D FSE in nearly all tissues, including periprostatic fat (45 ± 12 vs. 31 ± 7, <italic>P</italic> < 0.01), gluteal fat (48 ± 8 vs. 41 ± 10, <italic>P</italic> = 0.12), right peripheral zone (20 ± 4 vs. 16 ± 8, <italic>P</italic> = 0.12), left peripheral zone (17 ± 2 vs. 12 ± 3, <italic>P</italic> < 0.01), and anterior fibromuscular stroma (12 ± 4 vs. 4 ± 2, <italic>P</italic> < 0.01).</p> </sec> <sec id="mrm25430-sec-0004" sec-type="section"> <title>Conclusion</title> <p>3D T<sub>2</sub>‐TIDE images of the prostate can be acquired quickly with SNR efficiency that exceeds that of 3D FSE. Magn Reson Med 74:442–451, 2015. © 2014 Wiley Periodicals, Inc.</p> </sec> </abstract>