Combined assessment of WT1 and BAALC gene expression at diagnosis may improve leukemia-free survival prediction in patients with myelodysplastic syndromes. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Minetto, Paola; Guolo, Fabio; Clavio, Marino; De Astis, Enrico; Colombo, Nicoletta; Grasso, Raffaella; Fugazza, Giuseppina; Sessarego, Mario; Lemoli, Roberto Massimo; Gobbi, Marco; Miglino, Maurizio
• Is Part Of: Leukemia research. Volume 39:Issue 8(2015:Aug.)
• Page Start: 866
• Page End: 873
• Publication Date: 2015-08
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.04.011
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We analyzed WT1 and BAALC expression levels in MDS patients and diagnosis.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">WT1 and BAALC combined assessment independently correlated with LFS duration.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Molecular evaluation could further improve IPSS and R-IPSS stratification.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Adding molecular data to standard prognostic score may help therapeutic choices.</p> </list-item> </list> </p> </sec> </abstract>