HOXA9 and MEIS1 gene overexpression in the diagnosis of childhood acute leukemias: Significant correlation with relapse and overall survival. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Adamaki, Maria; Lambrou, George I.; Athanasiadou, Anastasia; Vlahopoulos, Spiros; Papavassiliou, Athanasios G.; Moschovi, Maria
• Is Part Of: Leukemia research. Volume 39:Issue 8(2015:Aug.)
• Page Start: 874
• Page End: 882
• Publication Date: 2015-08
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.04.012
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">HOXA9, MEIS1 expression is associated with of leukemic subtypes.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">HOXA9, MEIS1 expression is associated with maturation stages of ALL.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">HOXA9 and MEIS1 overexpression are inversely correlated with relapse in ALL.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">HOXA9 and MEIS1 overexpression are inversely correlated with overall survival in ALL.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">HOXA9 and MEIS1could become useful predictive markers of the clinical course of ALL.</p> </list-item> </list> </p> </sec> </abstract>