Energy intake, nonexercise physical activity, and weight loss in responders and nonresponders: The Midwest Exercise Trial 2. (August 2015)

• Record Type: Journal Article
• Authors: Herrmann, Stephen D.; Willis, Erik A.; Honas, Jeffery J.; Lee, Jaehoon; Washburn, Richard A.; Donnelly, Joseph E.
• Is Part Of: Obesity. Volume 23:Number 8(2015:Aug.)
• Page Start: 1539
• Page End: 1549
• Publication Date: 2015-08
• Subjects: Obesity -- Periodicals; 616.398005
• DOI: 10.1002/oby.21073
• Languages: English
• ISSNs: 1930-7381

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="oby21073-sec-0001" sec-type="section"> <title>Objective</title> <p>To compare energy intake, total daily energy expenditure (TDEE), nonexercise energy expenditure (NEEx), resting metabolic rate (RMR), nonexercise physical activity (NEPA), and sedentary time between participants with weight loss <5% (nonresponders) vs. ≥5% (responders) in response to exercise.</p> </sec> <sec id="oby21073-sec-0002" sec-type="section"> <title>Methods</title> <p>Adults (18‐30 years) with overweight/obesity (BMI 25‐40 kg/m<sup>2</sup>) were randomized to exercise: 5 days/week, 400 or 600 kcal/session, 10 months.</p> </sec> <sec id="oby21073-sec-0003" sec-type="section"> <title>Results</title> <p>Of the participants, 40 responded and 34 did not respond to the exercise protocol. Nonresponder energy intake was higher vs. responders, significant only in men (<italic>P</italic>=0.034). TDEE increased only in responders (<italic>P</italic>=0.001). NEEx increased in responders and decreased in nonresponders, significant only in men (<italic>P</italic>=0.045). There were no within‐ or between‐group differences for change in RMR. NEPA increased in responders and decreased in nonresponders (group‐by‐time interactions: total sample, <italic>P</italic>=0.049; men, <italic>P</italic>=0.016). Sedentary time decreased in both groups, significant only in men.</p> </sec> <sec id="oby21073-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Men who did not lose weight in response to exercise (<5%) had higher energy intake and lower NEEx when compared with men losing ≥5%. No significant differences in any parameters assessed were observed between women who lost <5% vs. those losing ≥5%. Factors associated with the weight loss response to exercise in women warrant additional investigation.</p> </sec> </abstract>