Consistent intensity inhomogeneity correction in water–fat MRI. Issue 2 (30th October 2014)

• Record Type: Journal Article
• Authors: Andersson, Thord; Romu, Thobias; Karlsson, Anette; Norén, Bengt; Forsgren, Mikael F.; Smedby, Örjan; Kechagias, Stergios; Almer, Sven; Lundberg, Peter; Borga, Magnus; Leinhard, Olof Dahlqvist
• Is Part Of: Journal of magnetic resonance imaging. Volume 42:Issue 2(2015)
• Page Start: 468
• Page End: 476
• Publication Date: 2014-10-30
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24778
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24778-sec-0001" sec-type="section"> <title>Purpose</title> <p>To quantitatively and qualitatively evaluate the <italic>water</italic>‐signal performance of the consistent intensity inhomogeneity correction (CIIC) method to correct for intensity inhomogeneities</p> </sec> <sec id="jmri24778-sec-0002" sec-type="section"> <title>Methods</title> <p>Water<bold>–</bold>fat volumes were acquired using 1.5 Tesla (T) and 3.0T symmetrically sampled 2‐point Dixon three‐dimensional MRI. Two datasets: (i) 10 muscle tissue regions of interest (ROIs) from 10 subjects acquired with both 1.5T and 3.0T whole‐body MRI. (ii) Seven liver tissue ROIs from 36 patients imaged using 1.5T MRI at six time points after Gd‐EOB‐DTPA injection. The performance of CIIC was evaluated quantitatively by analyzing its impact on the dispersion and bias of the water image ROI intensities, and qualitatively using side‐by‐side image comparisons.</p> </sec> <sec id="jmri24778-sec-0003" sec-type="section"> <title>Results</title> <p>CIIC significantly ( <inline-formula><alternatives><inline-graphic mimetype="image" xlink:href="ark:/27927/pgj22d5sm4w" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /><mml:math display="inline" altimg="urn:x-wiley:10531807:media:jmri24778:jmri24778-math-0001" overflow="scroll" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mi>P</mml:mi><mml:mrow><mml:mn>1</mml:mn><mml:mo>.</mml:mo><mml:mn>5</mml:mn><mml:mi mathvariant="normal">T</mml:mi></mml:mrow></mml:msup><mml:mo>≤</mml:mo><mml:mn>2.3</mml:mn><mml:mo>×</mml:mo><mml:msup><mml:mrow><mml:mn>10</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo><mml:mn>4</mml:mn></mml:mrow></mml:msup><mml:mo>, </mml:mo><mml:msup><mml:mi>P</mml:mi><mml:mrow><mml:mn>3</mml:mn><mml:mo>.</mml:mo><mml:mn>0</mml:mn><mml:mi mathvariant="normal">T</mml:mi></mml:mrow></mml:msup><mml:mo>≤</mml:mo><mml:mn>1.0</mml:mn><mml:mo>×</mml:mo><mml:msup><mml:mrow><mml:mn>10</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo><mml:mn>6</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math></alternatives></inline-formula>) decreased the nonphysiological intensity variance while preserving the average intensity levels. The side‐by‐side comparisons showed improved intensity consistency ( <inline-formula><alternatives><inline-graphic mimetype="image" xlink:href="ark:/27927/pgj22d5skzm" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /><mml:math display="inline" altimg="urn:x-wiley:10531807:media:jmri24778:jmri24778-math-0002" overflow="scroll" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mi>P</mml:mi><mml:mrow><mml:mi>int</mml:mi><mml:mo>⁡</mml:mo></mml:mrow></mml:msup><mml:mo>≤</mml:mo><mml:msup><mml:mrow><mml:mn>10</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo><mml:mn>6</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math></alternatives></inline-formula>) while not introducing artifacts ( <inline-formula><alternatives><inline-graphic mimetype="image" xlink:href="ark:/27927/pgj22d5skx2" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /><mml:math display="inline" altimg="urn:x-wiley:10531807:media:jmri24778:jmri24778-math-0003" overflow="scroll" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mi>P</mml:mi><mml:mrow><mml:mtext>art</mml:mtext></mml:mrow></mml:msup><mml:mo>=</mml:mo><mml:mn>0.024</mml:mn></mml:mrow></mml:math></alternatives></inline-formula>) nor changed appearances ( <inline-formula><alternatives><inline-graphic mimetype="image" xlink:href="ark:/27927/pgj22d5sm17" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /><mml:math display="inline" altimg="urn:x-wiley:10531807:media:jmri24778:jmri24778-math-0004" overflow="scroll" xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:mrow><mml:msup><mml:mi>P</mml:mi><mml:mrow><mml:mtext>app</mml:mtext></mml:mrow></mml:msup><mml:mo>≤</mml:mo><mml:msup><mml:mrow><mml:mn>10</mml:mn></mml:mrow><mml:mrow><mml:mo>−</mml:mo><mml:mn>6</mml:mn></mml:mrow></mml:msup></mml:mrow></mml:math></alternatives></inline-formula>).</p> </sec> <sec id="jmri24778-sec-0004" sec-type="section"> <title>Conclusion</title> <p>CIIC improves the spatiotemporal intensity consistency in regions of a homogenous tissue type. J. Magn. Reson. Imaging 2015;42:468–476.</p> </sec> </abstract>