A bioactive molecule in a complex wound healing process: platelet‐derived growth factor. (14th October 2014)

• Record Type: Journal Article
• Authors: Kaltalioglu, Kaan; Coskun‐Cevher, Sule
• Is Part Of: International journal of dermatology. Volume 54:Number 8(2015:Aug.)
• Page Start: 972
• Page End: 977
• Publication Date: 2014-10-14
• Subjects: Dermatology -- Periodicals; 616.5
• DOI: 10.1111/ijd.12731
• Languages: English
• ISSNs: 0011-9059

Abstract

<abstract abstract-type="main" id="ijd12731-abs-0001"> <title>Abstract</title> <p>Wound healing is considered to be particularly important after surgical procedures, and the most important wounds related to surgical procedures are incisional, excisional, and punch wounds. Research is ongoing to identify methods to heal non‐closed wounds or to accelerate wound healing; however, wound healing is a complex process that includes many biological and physiological events, and it is affected by various local and systemic factors, including diabetes mellitus, infection, ischemia, and aging. Different cell types (such as platelets, macrophages, and neutrophils) release growth factors during the healing process, and platelet‐derived growth factor is a particularly important mediator in most stages of wound healing. This review explores the relationship between platelet‐derived growth factor and wound healing.</p> </abstract>