Proteomic methods for biomarker discovery and validation. Are we there yet?. (August 2015)

• Record Type: Journal Article
• Authors: Hathout, Yetrib
• Is Part Of: Expert review of proteomics. Volume 12:Number 4(2015)
• Page Start: 329
• Page End: 331
• Publication Date: 2015-08
• Subjects: Proteins -- Biotechnology -- Periodicals; Proteomics -- Periodicals; 572.6
• DOI: 10.1586/14789450.2015.1064771
• Languages: English
• ISSNs: 1478-9450

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Noninvasive molecular biomarkers are becoming attractive tools to monitor disease progression, aid drug development programs and use as surrogate outcome measures in clinical trials. Cutting edge proteomic methods to assay biomarkers in body fluids have been developed in the past few years, but transitioning them to clinical practice has been slow and depends on the qualification of both the method and the biomarker.</p> </abstract>