A doubly responsive probe for the detection of Cys4-tagged proteins1. Issue 57 (21st July 2015)

• Record Type: Journal Article
• Authors: Kotera, N.; Dubost, E.; Milanole, G.; Doris, E.; Gravel, E.; Arhel, N.; Brotin, T.; Dutasta, J.-P.; Cochrane, J.; Mari, E.; Boutin, C.; Léonce, E.; Berthault, P.; Rousseau, B.
• Is Part Of: Chemical communications. Volume 51:Issue 57(2015)
• Page Start: 11482
• Page End: 11484
• Publication Date: 2015-07-21
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c5cc04721h
• Languages: English
• ISSNs: 1359-7345

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj1xv5d34b" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A biosensor for bimodal detection of recombinant Cys-tagged proteins <italic>via</italic> fluorescence and hyperpolarized ¹²⁹Xe NMR is presented. Interaction with a peptide containing the motif Cys–Cys–X–X–Cys–Cys activates both fluorescence and NMR responses.</p> </abstract>