Genotoxic and oxidative responses in coelomocytes of Eisenia fetida and Hediste diversicolor exposed to lipid‐coated CdSe/ZnS quantum dots and CdCl2. Issue 8 (5th February 2014)

• Record Type: Journal Article
• Authors: Saez, Gladys; Aye, Mélanie; De Meo, Michel; Aimé, Ahissan; Bestel, Isabelle; Barthélémy, Philippe; Di Giorgio, Carole
• Is Part Of: Environmental toxicology. Volume 30:Issue 8(2015:Aug.)
• Page Start: 918
• Page End: 926
• Publication Date: 2014-02-05
• Subjects: Water quality bioassay -- Periodicals; Water -- Pollution -- Toxicology -- Periodicals; Microbiological assay -- Periodicals; Toxicity testing -- Periodicals; Environmental toxicology -- Periodicals; Environmental Pollution -- Periodicals; Environmental Pollutants -- Periodicals; Environmental Monitoring -- Periodicals; Écotoxicologie -- Périodiques; Pollution -- Périodiques; 615.902
• DOI: 10.1002/tox.21966
• Languages: English
• ISSNs: 1520-4081

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <p>The emerging of Quantum Dots utilization in industrial or medicinal fields involved a potentially increase of these nanoparticles in environment. In this work, the genotoxic (comet assay) and oxidative effects (SOD activity, TBARS) of functionalized‐QDs and cadmium chloride were investigated on <italic>Hediste diversicolor</italic> and <italic>Eisenia fetida</italic> coelomocytes. Results demonstrated that functionalized‐QDs (QDNs) and cadmium chloride induced DNA damages through different mechanisms that depended on the nano‐ or ionic nature of Cd. The minimal genotoxic concentrations for <italic>H. diversicolor</italic> (&lt;0.001ng/g for QDNs and CdCl₂) were lower than for <italic>E. fetida</italic> (between 0.01 and 0.1 ng/g for QDNs, and between 0.001 and 0.01 ng/g for CdCl₂). These results showed that <italic>H. diversicolor</italic> was more sensitive than <italic>E. fetida</italic>. The two contaminants had a low impact on the oxidative stress markers. © 2014 Wiley Periodicals, Inc. Environ Toxicol 30: 918–926, 2015.</p> </abstract>