Drosophila melanogaster: a model organism for controlling Dipteran vectors and pests. (June 2015)

• Record Type: Journal Article
• Authors: Zolfaghari Emameh, Reza; Syrjänen, Leo; Barker, Harlan; Supuran, Claudiu T.; Parkkila, Seppo
• Is Part Of: Journal of enzyme inhibition and medicinal chemistry. Volume 30:Number 3(2015:Jun.)
• Page Start: 505
• Page End: 513
• Publication Date: 2015-06
• Subjects: Enzyme inhibitors -- Periodicals; Enzyme Inhibitors -- periodicals; Biochemistry -- periodicals; 572.7
• DOI: 10.3109/14756366.2014.944178
• Languages: English
• ISSNs: 1475-6366

Abstract

<abstract> <title>Abstract</title> <p>Beta-carbonic anhydrases (β-CAs) have been recently reported to be present in many protozoan and metazoan species, whereas it is absent in mammals. In this review, we introduce β-CA from <italic>Drosophila melanogaster</italic> as a model enzyme for pesticide development. These enzymes can be targeted with various enzyme inhibitors, which can have deleterious effects on pathogenic and other harmful organisms. Therefore, β-CAs represent a new potential target to fight against <italic>Dipteran</italic> vectors and pests relevant to medicine, veterinary medicine, and agriculture.</p> </abstract>