A prospective randomized blinded clinical trial: large‐volume nasal irrigation with fluticasone propionate in the early postoperative period following septoplasty. Issue 7 (6th April 2015)

• Record Type: Journal Article
• Authors: Tugrul, Selahattin; Dogan, Remzi; Senturk, Erol; Eren, Sabri Baki; Meric, Aysenur; Ozturan, Orhan
• Is Part Of: International forum of allergy & rhinology. Volume 5:Issue 7(2015:Jul.)
• Page Start: 610
• Page End: 615
• Publication Date: 2015-04-06
• Subjects: 617.51005
• DOI: 10.1002/alr.21527
• Languages: English
• ISSNs: 2042-6976

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="alr21527-sec-0010" sec-type="section"> <title>Background</title> <p>The aim of this study was to compare 2 methods of nasal irrigation after septoplasty. The combined use of low‐pressure, high‐volume nasal saline (LPHVNS) irrigation, together with fluticasone propionate (FP) (LPHVNS+FP), was compared with high‐pressure, low‐volume nasal saline (HPLVNS) irrigation during the early postoperative period following septoplasty.</p> </sec> <sec id="alr21527-sec-0020" sec-type="section"> <title>Methods</title> <p>Seventy‐three patients undergoing septoplasty for nasal obstruction were recruited for the study. The patients were randomly divided into 2 groups; nasal irrigation was applied for 4 weeks in both groups. Group 1 (n = 40) used HPLVNS irrigation. Group 2 (n = 33) used the LPHVNS+FP combination. The patients were evaluated using the visual analogue scale (VAS), Nasal Obstruction Symptom Evaluation (NOSE), nasal examination scores, acoustic rhinometry, rhinomanometry, and peak nasal inspiratory flowmetry (PNIF) measurements.</p> </sec> <sec id="alr21527-sec-0030" sec-type="section"> <title>Results</title> <p>In group 2, the increase in VAS results was more prominent than in group 1. NOSE scores were significantly lower in group 2 than in group 1. The nasal examination revealed that group 2 had less edema and less crusting than group 1. The decrease in nasal airway resistance was significantly higher in group 2. The PNIF values increased to a significantly greater extent in group 2 than in group 1.</p> </sec> <sec id="alr21527-sec-0040" sec-type="section"> <title>Conclusion</title> <p>Nasal irrigation with the LPHVNS+FP combination during the early postoperative period following septoplasty is an effective method, resulting not only in increased patient satisfaction and nasal air flow but also in decreased edema and crust formation.</p> </sec> </abstract>