Target selection for FDA-approved medicines. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Kinch, Michael S.; Hoyer, Denton; Patridge, Eric; Plummer, Mark
• Is Part Of: Drug discovery today. Volume 20:Issue 7(2015)
• Page Start: 784
• Page End: 789
• Publication Date: 2015-07
• Subjects: Drugs -- Design -- Periodicals; Drugs -- Research -- Periodicals; 615.1
• DOI: 10.1016/j.drudis.2014.11.001
• Languages: English
• ISSNs: 1359-6446

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Three target families dominate FDA-approved drugs, capturing almost half of all NMEs.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The fraction of NMEs targeting unknown mechanisms has remained steady over time.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Targeting novel mechanisms has increased progressively.</p> </list-item> </list> </p> </sec> </abstract>