Urocortin 2 in cardiovascular health and disease. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Adão, Rui; Santos-Ribeiro, Diana; Rademaker, Miriam T.; Leite-Moreira, Adelino F.; Brás-Silva, Carmen
• Is Part Of: Drug discovery today. Volume 20:Issue 7(2015)
• Page Start: 906
• Page End: 914
• Publication Date: 2015-07
• Subjects: Drugs -- Design -- Periodicals; Drugs -- Research -- Periodicals; 615.1
• DOI: 10.1016/j.drudis.2015.02.012
• Languages: English
• ISSNs: 1359-6446

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0230">Urocortin (Ucn)-2 regulates cardiac function.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0235">Ucn-2/CRH-R2 system activation promotes a consistent relaxation of the vessels.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0240">Animal studies have shown beneficial therapeutic effects of Ucn-2 in heart failure.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0245">Therapeutic benefits of Ucn-2 have also been shown in patients with heart failure.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0250">Ucn-2 is emerging as a promising therapeutic option for cardiovascular diseases.</p> </list-item> </list> </p> </sec> </abstract>