A Review: The Pharmacology of Isoliquiritigenin. (24th April 2015)

• Record Type: Journal Article
• Authors: Peng, Fu; Du, Qiaohui; Peng, Cheng; Wang, Neng; Tang, Hailin; Xie, Xiaoming; Shen, Jiangang; Chen, Jianping
• Is Part Of: Phytotherapy research. Volume 29:Number 7(2015:Jul.)
• Page Start: 969
• Page End: 977
• Publication Date: 2015-04-24
• Subjects: Materia medica, Vegetable -- Periodicals; Botany, Medical -- Periodicals; Medicinal plants -- Periodicals; Plant Extracts -- therapeutic use -- Periodicals; Plants, Medicinal -- Periodicals; 581.634
• DOI: 10.1002/ptr.5348
• Languages: English
• ISSNs: 0951-418X

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Isoliquiritigenin (ISL) is one of the bioactive ingredients isolated from the roots of plants belonging to licorice, including <italic>Glycyrrhiza uralensis</italic>, <italic>Mongolian glycyrrhiza</italic>, <italic>Glycyrrhiza glabra</italic>, and so forth. Liquiritigenin is available in common foods and alternative medicine, and its derivative‐ISL is applied into food additives and disease treatment like cancer therapy, antibiotic therapy, and so on. This review aims at providing a comprehensive summary of the pharmacological activities of ISL. The information published between 1972 and 2014 from a number of reliable sources including PubMed, ScienceDirect, Springer, and Wiley‐Blackwell. The practical application of ISL on the various disease prevention and treatments may stem from its numerous pharmacological properties such as antiinflammatory, anti‐microbial, anti‐oxidative, anticancer activities, immunoregulatory, hepatoprotective, and cardioprotective effects. However, further studies are needed to verify the target‐organ toxicity or side effects investigation. Copyright © 2015 John Wiley &amp; Sons, Ltd.</p> </abstract>