Selective laser sintering manufacturing of polycaprolactone bone scaffolds for applications in bone tissue engineering. Issue 4 (15th June 2015)

• Record Type: Journal Article
• Authors: Mazzoli, Alida; Ferretti, C; Gigante, A; Salvolini, E; Mattioli-Belmonte, M
• Is Part Of: Rapid prototyping journal. Volume 21:Issue 4(2015)
• Page Start: 386
• Page End: 392
• Publication Date: 2015-06-15
• Subjects: Engineering design -- Periodicals; 620.004205
• DOI: 10.1108/RPJ-04-2013-0040
• Languages: English
• ISSNs: 1355-2546

Abstract

<abstract> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <sec> <title content-type="abstract-heading">Purpose</title> <p> – The purpose of this study is to show how selective laser sintering (SLS) manufacturing of bioresorbable scaffolds is used for applications in bone tissue engineering. </p> </sec> <sec> <title content-type="abstract-heading">Design/methodology/approach</title> <p> – Polycaprolactone (PCL) scaffolds were computationally designed and then fabricated via SLS for applications in bone and cartilage repair. </p> </sec> <sec> <title content-type="abstract-heading">Findings</title> <p> – Preliminary biocompatibility data were acquired using human mesenchymal stem cells (hMSCs) assuring a satisfactory scaffold colonization by hMSCs. </p> </sec> <sec> <title content-type="abstract-heading">Originality/value</title> <p> – A promising procedure for producing porous scaffolds for the repair of skeletal defects, in tissue engineering applications, was developed.</p> </sec> </abstract>