Advances in the understanding of the clinically relevant genetic pathways and molecular aspects of canine mammary tumours: Part 1. Proliferation, apoptosis and DNA repair. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Matos, A.J.F.; Santos, A.A.
• Is Part Of: Veterinary journal. Volume 205:Issue 2(2015)
• Page Start: 136
• Page End: 143
• Publication Date: 2015-08
• Subjects: Veterinary medicine -- Periodicals; 636
• DOI: 10.1016/j.tvjl.2015.02.004
• Languages: English
• ISSNs: 1090-0233

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">New canine mammary tumour treatments must rely on solid knowledge of their biology.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Recent advances have been made in the understanding of their pathways.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">TP53/P53, PR, and Ki-67 are the most valuable prognostic factors for CMT.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">HER-2, ER and AgNOR require standardisation of the evaluation methods.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030">Molecular phenotypes, telomerase and PTEN require validation in clinical trials.</p> </list-item> </list> </p> </sec> </abstract>