Acemannan accelerates cell proliferation and skin wound healing through AKT/mTOR signaling pathway. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Xing, Wei; Guo, Wei; Zou, Cun-Hua; Fu, Ting-Ting; Li, Xiang-Yun; Zhu, Ming; Qi, Jun-Hua; Song, Jiao; Dong, Chen-Hui; Li, Zhuang; Xiao, Yong; Yuan, Pei-Song; Huang, Hong; Xu, Xiang
• Is Part Of: Journal of dermatological science. Volume 79:Issue 2(2015:Aug.)
• Page Start: 101
• Page End: 109
• Publication Date: 2015-08
• Subjects: Dermatology -- Periodicals; Skin Diseases -- Periodicals; Dermatologie -- Périodiques; 616.5005
• DOI: 10.1016/j.jdermsci.2015.03.016
• Languages: English
• ISSNs: 0923-1811

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Acemannan promotes skin wound healing and cell proliferation in vivo.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Acemannan promotes cell proliferation by inducing cyclin D1 protein translation.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Acemannan promotes cyclin D1 protein translation by Akt/mTOR signaling.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Acemannan promotes fibroblasts proliferation by activation of Akt/mTOR signaling.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">Acemannan promotes skin wound healing by activation of mTOR signaling.</p> </list-item> </list> </p> </sec> </abstract>