The efficacy of TachoComb on reducing postoperative complications after tonsillectomy in children. Issue 8 (August 2015)

• Record Type: Journal Article
• Authors: Kim, Yong-Wan; Kang, Myoung-Joo; Lee, Hyung-Ju; Woo, Chang-Ki; Mun, Mi-Jin; Cho, Kyu-Sup
• Is Part Of: International journal of pediatric otorhinolaryngology. Volume 79:Issue 8(2015:Aug.)
• Page Start: 1337
• Page End: 1340
• Publication Date: 2015-08
• Subjects: Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Otolaryngology -- Periodicals; Pediatrics -- Periodicals; Oto-rhino-laryngologie -- Périodiques; Pédiatrie -- Périodiques; 618.9209751
• DOI: 10.1016/j.ijporl.2015.06.006
• Languages: English
• ISSNs: 0165-5876

Abstract

<abstract abstract-type="author" id="abs0005"> <title id="sect0005">Abstract</title> <sec> <title id="sect0010"> <bold>Objective</bold> </title> <p id="spar0005">A fibrinogen/thrombin-based collagen fleece (TachoComb) is a powerful topical hemostatic agent that has been widely used in various surgical specialties with a favorable outcome. The purpose of this study was to investigate the effect of TachoComb application on postoperative complications after tonsillectomy.</p> </sec> <sec> <title id="sect0015"> <bold>Materials and methods</bold> </title> <p id="spar0010">A total of 1633 children had undergone tonsillectomy with or without adenoidectomy were included in this study. After removal of both tonsils, 1057 patients (64.7%) were treated with TachoComb on the tonsillectomy site and 576 without TachoComb. Post-tonsillectomy pain, hemorrhage rates, re-admission rates, and emergency surgery rates for post-tonsillectomy hemorrhage were evaluated between patients who received TachoComb and those who did not.</p> </sec> <sec> <title id="sect0020"> <bold>Results</bold> </title> <p id="spar0015">TachoComb treatment significantly reduced post-tonsillectomy pain and emergency surgery rates for post-tonsillectomy hemorrhage. However, postoperative hemorrhage rate and re-admission rates for post-tonsillectomy hemorrhage were not statistically significant between TachoComb treatment group and control group. No patients had complications or adverse reactions after TachoComb treatment.</p> </sec> <sec> <title id="sect0025"> <bold>Conclusions</bold> </title> <p id="spar0020">The use of TachoComb after tonsillectomy significantly reduces pain and emergency surgery for severe post-tonsillectomy hemorrhage without an apparent adverse effect. Therefore, TachoComb may be a useful adjuvant in terms of efficacy and safety after tonsillectomy.</p> </sec> </abstract>