Design, synthesis and evaluation of MCH receptor 1 antagonists—Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414. Issue 16 (15th August 2015)

• Record Type: Journal Article
• Authors: Müller, Stephan G.; Heckel, Armin; Kley, Jörg T.; Lehmann, Thorsten; Lustenberger, Philipp; Oost, Thorsten; Roth, Gerald J.; Rudolf, Klaus; Arndt, Kirsten; Lenter, Martin; Lotz, Ralf R.H.; Maier, Gerd-Michael; Markert, Michael; Schindler, Marcus; Stenkamp, Dirk
• Is Part Of: Bioorganic & medicinal chemistry letters. Volume 25:Issue 16(2015)
• Page Start: 3264
• Page End: 3269
• Publication Date: 2015-08-15
• Subjects: Bioorganic chemistry -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1016/j.bmcl.2015.05.077
• Languages: English
• ISSNs: 0960-894X

Abstract

<abstract xml:lang="en" abstract-type="graphical" id="ab005"> <title id="st005">Graphical abstract</title> <sec> <p id="sp0005"> <fig id="f0060" position="anchor"> <graphic position="anchor" xlink:href="ark:/27927/pgj1d33gfd6" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /> </fig> </p> </sec> </abstract>