Dopamine Electroanalysis Using Electrochemical Biosensors Prepared by a Sinusoidal Voltages Method. Issue 7 (16th April 2015)

• Record Type: Journal Article
• Authors: Lupu, Stelian; Lete, Cecilia; Javier del Campo, Francisco
• Is Part Of: Electroanalysis. Volume 27:Issue 7(2015:Jul.)
• Page Start: 1649
• Page End: 1659
• Publication Date: 2015-04-16
• Subjects: Electrochemical analysis -- Periodicals; Chemistry, Analytical -- Periodicals; Electrochemistry -- Periodicals; 543.4
• DOI: 10.1002/elan.201400680
• Languages: English
• ISSNs: 1040-0397

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A biocomposite material of tyrosinase and poly(3, 4‐ethylenedioxythiophene) was electrodeposited onto gold (Au) disk microelectrode arrays and Au interdigitated microband electrode arrays (IDEs) by using a combination of sinusoidal voltages and microgravimetric method to construct amperometric biosensors for dopamine (DA). The main advantage of this new strategy consists in a reliable enzyme immobilization and in additional information related to the electropolymerization process. The determination of DA was successfully achieved in pharmaceutical formulations. The best analytical performances, in terms of the lowest limit of detection of 6×10⁻⁷ M DA and highest recovery and stability, were obtained for IDEs based biosensor.</p> </abstract>