The emperor's new dystrophin: finding sense in the noise. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Wilton, S.D.; Veedu, R.N.; Fletcher, S.
• Is Part Of: Trends in molecular medicine. Volume 21:Issue 7(2015)
• Page Start: 417
• Page End: 426
• Publication Date: 2015-07
• Subjects: Molecular biology -- Periodicals; Pathology, Molecular -- Periodicals; Physiology, Pathological -- Periodicals; 572.8
• DOI: 10.1016/j.molmed.2015.04.006
• Languages: English
• ISSNs: 1471-4914

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Dystrophin restoring therapy should increase dystrophin expression after treatment.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Restoration of functional dystrophin will take months to result in clinical benefit.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Eteplirsen-treated DMD boys show slower disease progression than predicted from the natural history.</p> </list-item> </list> </p> </sec> </abstract>