Plexin-B1 and semaphorin 4D cooperate to promote cutaneous squamous cell carcinoma cell proliferation, migration and invasion. Issue 2 (August 2015)

• Record Type: Journal Article
• Authors: Cao, Jiao; Zhang, Chen; Chen, Ting; Tian, Rong; Sun, Shuhong; Yu, Xianshui; Xiao, Chunying; Wang, Gang; Liu, Yufeng; Fu, Meng; Li, Wei
• Is Part Of: Journal of dermatological science. Volume 79:Issue 2(2015:Aug.)
• Page Start: 127
• Page End: 136
• Publication Date: 2015-08
• Subjects: Dermatology -- Periodicals; Skin Diseases -- Periodicals; Dermatologie -- Périodiques; 616.5005
• DOI: 10.1016/j.jdermsci.2015.05.002
• Languages: English
• ISSNs: 0923-1811

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Expression of Plexin-B1 and Sema4D were increased in keratinocytes in cSCC lesions.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Sema4D induces cSCC cell proliferation, migration, and invasion by interacting with Plexin-B1 expressed on cSCC cells.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Akt and Erk phosphorylation are involved in Plexin-B1 mediated function.</p> </list-item> </list> </p> </sec> </abstract>